Endocrine Abstracts

Introduction: Primary hyperparathyroidism (PHPT) is most commonly sporadic and in rare circumstances, it can develop as part of multiple endocrine neoplasia (MEN). There are few cases described in the literature reporting an association of PHPT with myasthenia gravis and multiple autoimmune syndrome (MAS). These patients may present only with clinical signs of PHPT making it difficult to suspect the coexistence of MAS. Here, we report the case of type 3 MAS in a woman with PHP...

Introduction: Many thyroid conditions are associated with the development of a rapidly progressing goiter and should evoke several diagnoses, some of which may be of poor prognosis.Case-presentation: A 47-year-old female patient with no previous pathological history presented with a large goiter associated with a deteriorated general condition that had been evolving for 3 weeks On examination, she presented with a fever at 39°C, multiple cervical ad...

Introduction: Thyrotropin deficiency is a rare etiology of hypothyroidism. The diagnosis can be easily confirmed in case of low FT4 level associated with normal or low TSH value. In patients with peripheral hypothyroidism treated by levothyroxine, this biochemical profile become difficult to find. Herein, we describe the case of a patient with peripheral hypothyroidism due to radioiodine therapy in whom the diagnosis of central hypothyroidism was made.Ob...

Introduction: Neurofibromatosis type 1 (NF1) is a rare autosomal dominant disease. Patients affected by NF1 have an increased risk of developing tumors other than neurofibromas, especially of endocrine origin, that’s why this patients should be screened for endocrine lesions. In this report, we describe a patient affected by NF1 who present a thyroid nodule.Observation: A 27-year-old woman was admitted in our department for endocrinological evaluati...

Introduction: Acromegaly is the set of clinical manifestations induced by chronic exposure to an endogenous excess of growth hormone (GH). Most often, acromegaly is related to GH production by a pituitary adenoma. It may be associated with neuroendocrine tumors of the pancreas as part of multiple endocrine neoplasia type 1 (MEN1). Herein, we described a tumor mimicking a carcinoma of the Ampulla of Vater in a patient with acromegaly.Observation: A 54-yea...

Introduction: Diabetic foot is known to represent a serious complication of diabetes mellitus, responsible for significant morbidity, disability and considerable financial implications. The prevention of this complication requires, first and foremost, a good patient education.Objective: To evaluate the current state of knowledge and practices of foot care in diabetic patients and to identify factors associated with a good educational level.<p class="...

Introduction: The otorhinolaryngologist can be confronted to multiple surprises after a thyroid surgeryCase description: We report the case of a 48 year-old woman admitted with post operative hypocalcaemia (after thyroidectomy?). The patient has a history of hypothyroidism since 5 years. She then presented a cervical swelling. The ultra-sound confirmed the presence of a suspicious thyroid nodule measuring 4 cm. A thyroidectomy was then conducted. Post op...

Introduction: The association of primary hyperparathyroidism (PHPT) and hyperthyroidism secondary to toxic multinodular goiter (TMNG) is rarely described in the literature. Hereby, we describe the clinical, biological, and radiological characteristics of two patients having this rare association.Observations: First case: A 66 years-old female was diagnosed with primary hyperthyroidism. Her thyroid antibodies were negatives. During the follow-up, she pres...

Introduction: Chromosomal abnormality 47, XYY, despite being present in approximately 1 in 1000 newborn boys, remains less known phenotypically and more than 85% of men are never diagnosed. Males with 47, XYY syndrome are described to be phenotypically normal. They present often a developmental delay, behavioral difficulties and learning disabilities that may be associated with accelerated growth rate and taller stature in adulthood. Endocrine disorders, especially pubertal de...

Introduction: Hyperpigmentation is a clinical sign that can be associated with different endocrine disorders. It is commonly seen in Addison’s disease and has rarely been reported in Graves’ disease. The exact physio pathological mechanism of this sign is not well established in hyperthyroidism. We describe two cases of Graves’ disease accompanied by diffuse hyperpigmentation.Case report: Case 1 was a 63-year-old female ad...